
Semaglutide vs. Tirzepatide: A Physician’s Guide to GLP-1 Weight-Loss Medications
By Dr. Shiv Kumar Goel, MD · Medically Reviewed & Updated 2026-07-29
In the treatment of metabolic resistance and obesity, Semaglutide and Tirzepatide represent two landmark advancements in incretin-based pharmacotherapy. As a Mount Sinai-trained physician, Dr. Shiv Kumar Goel, MD integrates these medications into comprehensive physician-led medical weight loss protocols in San Antonio, ensuring that patients achieve fat loss while preserving lean skeletal muscle mass.